Publications in Journals
A. Körtge, P. Elter, R. Lange, U. Beck
Simulation of the Electric Field Distribution Near a Topographically Nanostructured Titanium-Electrolyte Interface: Influence of the Passivation Layer
J Nanomater 2013, Article ID 820914
P. Elter, T Weihe, S. Bühler, J. Gimsa, U. Beck
Low fibronectin concentrations overcompensate for reduced initial fibroblasts adhesion to a nanoscale topography: single-cell force spectroscopy
Colloids and Surfaces B: Biointerfaces 95 (2012) 82-89
P. Elter, R. Lange, U. Beck
Atomic force microscopy studies of the influence of convex and concave nanostructures on the adsorption of fibronectin
Colloids and Surfaces B: Biointerfaces 89 (2012) 139– 146
D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic, A. Iglic
Attachment of Rod-Like (BAR) Proteins and Membrane Shape
Mini-Rev. Med. Chem. 11 (2011) p. 272-282
Gongadze E, Perutkovà Š, Kralj-Iglic V, van Rienen U, Beck U, Iglic A, Kabaso D,
Electromechanical basis for the interaction between osteoblasts and negatively charged titanium surface
Advances in Planar Lipid Bilayers and Liposomes (APLBL), 13/6 (2011) 197-219
P. Elter, R. Lange, U. Beck
Electrostatic and Dispersion Interactions during Protein Adsorption on Topographic Nanostructures
Langmuir 27 (2011) pp. 8767-8775
Elter P, Weihe T, Lange R, Gimsa J, Beck U
The influence of topographic microstructures on the initial adhesion of L929 fibroblasts studied by single-cell force spectroscopy
European Biophysics Journal 40 (2011), iss.3, 317
D. Kabaso, E. Gongadze, S. Perutkova, C. Matschegewski, V. Kralj-Iglic, U. Beck, U. van Rienen, A. Iglic
Mechanics and electrostatics of the interactions between osteoblasts and titanium surface
Computer Methods in Biomechanics and Biomedical Engineering, 14/5 (2011) 469-482.
T. Weihe, S. Bonk, P. Elter, J. Gimsa
Single-cell Force Spectroscopy for the determination of initial adhesion of cells to different surfaces
Biomed. Tech. 55 (2010):175-178
Kunz F, Bergemann C, Klinkenberg ED, Weidmann A, Lange R, Beck U, Nebe JB
A novel modular device for 3-D bone cell culture and non-destructive cell analysis
Acta Biomaterialia 6 (2010) 3798-3807
Matschegewski C, Staehlke S, Loeffler R, Lange R, Chai F, Kern DP, Beck U, Nebe BJ
Cell architecture - cell function dependencies on titanium arrays with regular geometry
Biomaterials 31 (2010) 5729-5740
Lange R, Elter P, Biala K, Matschegewski C, Stählke S, Löffler R, Fleischer M, Nebe JB, Kern D, Beck U
Titanium Surfaces Structured with Regular Geometry – Material Investigations and Cell Morphology
Surface and Interface Analysis 42 (2010) 497–501
Nebe J.B., Jesswein H., Weidmann A., Finke B., Lange R., Beck U., Schroeder K.
Osteoblast Sensitivity to Topographical and Chemical Features of Titanium
Materials Science Forum 638-642 (2010) 652-657
R. Rebentisch, R. Lange, U. Beck
Long-term corrosion resistance of biomedical grade stainless steel ISO 5832-1 (”316LVM”) under external anodic electrical pulsing conditions
Advanced Materials Research 89-91 (2010) 455-460
P. Elter, R. Lange, R. Thull, U.Beck
Protein adsorption on topographically structured surfaces: a mesoscopic computer simulation for the prediction of prefered adsorption sites
Materials Science Forum 638-642 (2010) 542-547
U. Beck, P. Elter, R. Lange, A. Ewald
Lamellar surface structures on stainless steel 316 LVM and their influence on osteoblastic cells
Materials Science Forum 638-642 (2010) 501-505
C. Bergemann, E.-D. Klinkenberg, F. Lüthen, A. Weidmann, R. Lange, U. Beck, R. Bader, K. Schröder, B. Nebe
Proliferation and migration of human osteoblasts on porous three dimensionalscaffolds
Materials Science Forum 638-642 (2010) 506-511
A. Weidmann, C. Matschegewski, R. Löffler, R. Lange, U. Beck, D. Kern, B. Nebe
Time dependent osteoblast response on defined microstructured titanium wafers
BIOmaterialien 10 (2009), S1, 93
R. Lange, P. Elter, C. Matschegewski, A. Weidmann, R. Löffler, M. Fleischer, J.B. Nebe, D. Kern, U. Beck
Material and cellbiological investigations on structured biomaterial surfaces with regular geometry
BIOmaterialien 10 (2009), S1, 84
C. Bergemann, E.-D. Klinkenberg, F. Lüthen, A. Weidmann, R. Lange, U. Beck, R. Bader, B. Nebe
Developement of a three dimensional tantalum model system in vitro to investigate the cell growth in the depth of the corpus
BIOmaterialien 10 (2009), S1, 54
Kasten A., Müller P., Bulnheim U., Kaminski A., Steinhoff G., Beck U., Rychly J.
Biological responses of mesenchymal stem cells induced by mechanical integrin stress
BIOmaterialien 10 (2009), S1, 43
Jesswein H., Finke B., Lange R., Stählke S., Beck U., Gimsa J., Schröder K., Nebe B.
Time dependent adhesion of vital human osteoblasts on positively charged plasma polymer coated surfaces
BIOmaterialien 10 (2009), S1, 75
U. Beck, R. Lange, U. Lembke, H.-G. Neumann
Three-Layer Coating for Stents with Nanostructured Surface
Key Engineering Materials 396-398 (2009), 627-630
P. Elter, F. Sickel, A. Ewald
Nanoscaled periodic surface structures of medical stainless steel and their effect on osteoblastic cells
Acta Biomaterialia 5 (2009), p.1468-1473
P. Elter, R. Thull
Release of antibiotic combinations from polymethylmethacrylate bone cement
Biomaterialien 10 (2009), 1/2, p. 18-24
U. Lembke, R. Lange, U. Beck, H.-G. Neumann
Nanostructured Calcium Phosphate Coating for Stents
Key Engineering Materials 361-363 (2008) 721-724
R. Lange, F. Lüthen, B. Nebe, U.Beck
European Cells & Materials 14 (2007) S3, 102
R. Lange, F. Lüthen, B. Nebe, J. Rychly, U. Beck
Mathematical correlation between biomaterial and cellular parameters - critical reflection of statistics
Biomolecular Engineering 24 (2007) 526-530
B. Nebe, F. Lüthen, R. Lange, U. Beck
Macromolecular Bioscience 7 (2007) 567-578
U. Beck, R. Lange, H.-G. Neumann
Micro- and nanoscaled titanium surface structures textured by electrolytic plasma and etching methods
Advanced Materials Research 15-17 (2007) 141-146
B. Nebe, F. Lüthen, R. Lange, U. Beck
Cellular activity and biomaterial’s surface topography
Materials Science Forum 539-543 (2007) 517-522
U. Beck, R. Lange, H.-G. Neumann
Micro-plasma textured Ti-implant surfaces
Biomolecular Engineering 24 (2007) 1, 47-51
R. Lange, F. Lüthen, B. Nebe, J. Rychly, U. Beck
Critical Reflection of the statistical correlation between biomaterial and cellular parameters
BIOmaterialien 7 (2006) S1, 86
B. Nebe, F. Lüthen, R. Lange, U. Bulnheim, P. Müller, H.-G. Neumann, J. Rychly, U. Beck
Interface interaction of osteoblasts with structured titanium surfaces
BIOmaterialien 6 (2005) 1, 35-41
U. Beck, R. Lange, H.-G. Neumann
Erzeugung von Nano-Strukturen an Titanoberflächen durch Mikroplasma-Verfahren
BIOmaterialien 6 (2005) 3, 164
A. Diener, B. Nebe, F. Lüthen, P. Becker, U. Beck, H.-G. Neumann, J. Rychly
Control of focal adhesion dynamics by material surface characteristics
Biomaterials 26 (2005) 4, 383-392
F. Lüthen, R. Lange, P. Becker, J. Rychly, U. Beck, B. Nebe
Biomaterials 26 (2005) 15, 2423-2440
B. Nebe, F. Lüthen, R. Lange, P. Becker, U. Beck, J. Rychly
Topography-induced alterations in adhesion structures affect mineralization in human osteoblasts on titanium
Materials Science and Engineering C 24 (2004) 619-624
R. Lange, F. Lüthen, A. Kirbs, A. Baumann, P. Müller, J. Rychly, B. Nebe, U. Beck
Correlation between physico-chemical properties of micro-structured implants and cell biological parameters
BIOmaterialien 5 (2004) S1, 74-75
B. Nebe, F. Lüthen, A. Diener, P. Becker, R. Lange, U. Beck, H.-G. Neumann, J. Rychly
Mechanisms of cell adhesion on surfaces of pure titanium
BIOmaterialien 5 (2004) S1, 32-33
A. Kirbs, R. Lange, B.Nebe, F. Lüthen, J. Rychly, U. Beck
Methods for the physical and chemical characterisation of surfaces of titanium implants
Materials Science and Engineering C 23 (2003) 425-429
A. Kirbs, R. Lange, B. Nebe, J. Rychly, P. Müller, U. Beck
On the description of the fractal nature of micro structured surfaces of titanium-implants
Materials Science and Engineering C 23 (2003) 413-418
R. Lange, F. Lüthen, U. Beck, J. Rychly, A. Baumann, B. Nebe
Cell-extracellular matrix interaction and physico-chemical characteristics of titanium surfaces depend on the roughness of the material
Biomolecular Engineering 19 (2002) 255-261
Book Chapters

B. Hoffmann, G. Ziegler, R. Lange, U. Beck
I.3.1 Patterning by mechanical treatment
In: Metallic Biomaterial Interfaces
Hrsg: J. Breme, C.J. Kirkpatrick, R. Thull
Wiley-VCH, Weinheim, 2008
F. Müller, S. Winter, U. Beck, R. Lange
I.3.2 Etching techniques
In: Metallic Biomaterial Interfaces
Hrsg: J. Breme, C.J. Kirkpatrick, R. Thull
Wiley-VCH, Weinheim, 2008
U. Beck, R. Lange
I.3.4 Plasma Processes
In: Metallic Biomaterial Interfaces
Hrsg: J. Breme, C.J. Kirkpatrick, R. Thull
Wiley-VCH, Weinheim, 2008
U. Beck, R. Lange
II.2 Surface Topology
In: Metallic Biomaterial Interfaces
Hrsg: J. Breme, C.J. Kirkpatrick, R. Thull
Wiley-VCH, Weinheim, 2008
U. Beck, R. Thull, R. Lange
II.3 Electrochemical characterization
In: Metallic Biomaterial Interfaces
Hrsg: J. Breme, C.J. Kirkpatrick, R. Thull
Wiley-VCH, Weinheim, 2008
Lectures/Posters
A. Körtge, U. Lembke, R. Lange, S. Stählke, B. Nebe, H.-G. Neumann, U. Beck
Surface Analysis of Ti and TiO2 Coatings made by Gas Flow Sputtering
24th European Conference on Biomaterials, Dublin, September 2011
R. Lange, R. Löffler, S. Stählke, P. Elter, B. Nebe, D. Kern and U. Beck
Microscopy Conference, Kiel, August 2011
R. Lange, K. Biala, U. Beck
23th European Conference on Biomaterials, Tampere, September 2010
R. Lange, P. Elter, K. Biala, C. Matschegewski, S. Stählke, R. Löffler, M. Fleischer, J.B. Nebe, D. Kern, U. Beck
Titanium Surfaces Structured with Regular Geometry – Material and Cell Biological Investigations
ECASIA’09, Antalya, Oktober 2009
P. Elter, A. Ewald, R. Lange, U. Beck
The influence of nanoscaled lamellar surface structures on osteoblastic cells
22th European Conference on Biomaterials, Lausanne, September 2009
R. Lange, P. Elter, C. Matschegewski, A. Weidmann, R. Löffler, M. Fleischer, J.B. Nebe, D. Kern, U. Beck
Material properties of Titanium surfaces with regular geometry and their influence on osteoblast behaviour
22th European Conference on Biomaterials, Lausanne, September 2009
Nebe J.B., Jesswein H., Weidmann A., Finke B., Lange R., Beck U., Schroeder K.
Osteoblast Sensitivity to Topographical and Chemical Features of Titanium
Thermec’, Berlin, August 2009
R. Rebentisch, R. Lange, U. Beck
Long-term corrosion resistance of biomedical grade stainless steel ISO 5832-1 (”316LVM”) under external anodic electrical pulsing conditions
Thermec’, Berlin, August 2009
P.Elter, R. Lange, R. Thull, U.Beck
Protein adsorption on topographically structured surfaces: a mesoscopic computer simulation for the prediction of prefered adsorption sites
Thermec’, Berlin, August 2009
U. Beck, P. Elter, R. Lange, A. Ewald
Lamellar surface structures on stainless steel 316 LVM and their influence on osteoblastic cells
Thermec’, Berlin, August 2009
C. Bergemann, E.-D. Klinkenberg, F. Lüthen, A. Weidmann, R. Lange, U. Beck, R. Bader, K. Schröder, B. Nebe
Proliferation and migration of human osteoblasts on porous three dimensional scaffolds
Thermec’, Berlin, August 2009
A. Weidmann, C. Matschegewski, R. Löffler, R. Lange, U. Beck, D. Kern, B. Nebe
Time dependent osteoblast response on defined microstructured titanium wafers
3. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2009
C. Bergemann, E.-D. Klinkenberg, F. Lüthen, A. Weidmann, R. Lange, U. Beck, R. Bader, B. Nebe
Developement of a three dimensional tantalum model system in vitro to investigate the cell growth in the depth of the corpus
3. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2009
R. Lange, P. Elter, C. Matschegewski, A. Weidmann, R. Löffler, M. Fleischer, J.B. Nebe, D. Kern, U. Beck
Material and cellbiological investigations on structured biomaterial surfaces with regular geometry
3. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2009
Kasten A., Müller P., Bulnheim U., Kaminski A., Steinhoff G., Beck U., Rychly J.
Biological responses of mesenchymal stem cells induced by mechanical integrin stress
3. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2009
Jesswein H., Finke B., Lange R., Stählke S., Beck U., Gimsa J., Schröder K., Nebe B.
Time dependent adhesion of vital human osteoblasts on positively charged plasma polymer coated surfaces
3. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2009
C. Matschegewski, A. Weidmann, R. Löffler, R. Lange, U. Beck, D. Kern, J. B. Nebe
Time dependent activation of intracellular signalling proteins in osteoblasts on microstructered titanium surfaces
Jahrestagung der Deutschen Gesellschaft für Zellbiologie, Konstanz, März 2009
H. Jesswein, A. Weidmann, B. Finke, R. Lange, U. Beck, L. Jonas, S. Staehlke, K. Schroeder, J.B. Nebe
Enhanced cell-material surface-contact due to positively charged plasma polymer coated titanium
Jahrestagung der Deutschen Gesellschaft für Zellbiologie, Konstanz, März 2009
P. Elter, B. Nebe, R. Lange, U. Beck
Osteoblastic cells on highly rough and/or porous implant surfaces
AFM BioMed Conference, Monterey, Oktober 2008
U. Beck, R. Lange, U. Lembke, H.-G. Neumann
Three-Layer Coating for Stents with Nanostructured Surface
Bioceramics 21, Buzios, Brasilien, Oktober 2008
U. Beck, R. Lange, H.-G. Neumann
Micro- and Nano-Textured Surfaces on Ti-Implants Made by Various Methods
14th European Microscopy Congress, Aachen, September 2008
U. Beck, R. Lange, H.-G. Neumann
Erzeugung mikro- und nanoskalierter Oberflächenstrukturen auf Titan mittels elektrolytischer Plasma- und Ätzmethoden
Thüringer Grenz- und Oberflächentage, Jena, September 2008
U. Beck, R. Lange, U. Lembke, H.-G. Neumann
Multilayer Coating for Stents with TiNbN, SiO2 Xerogel and Nanostrutured CaP
ICCE 16, Kunming, China, Juli 2008
U. Beck, R. Lange, M. Nowottnick
Tin Whiskers on Lead-Free Printed Circuit Board After Finishing
Intern. Conf. on Electronic Materials, Sydney, Juli 2008
U. Beck, R. Lange, U. Lembke, H.-G. Neumann
Multilayer Stent Coating with TiNbN and Nanostructured CaP
8th World Biomaterials Congress, Amsterdam, Mai 2008
U. Lembke, R. Lange, U. Beck, H.-G. Neumann
Nanostructured Calcium Phosphate Coating for Stents
Bioceramics 20, Nantes, Oktober 2007
R. Lange, F. Lüthen, B. Nebe, U.Beck
BIOSURF VII, Zürich, August 2007
U. Beck, R. Lange, U. Lembke, H.-G. Neumann
New coating for stents with nanostructured calcium phosphate
ICCE 15, Haikou, China, Juli 2007
U. Beck, R. Lange, H.-G. Neumann
New micro- and nanoscaled structures textured by electrochemical methods on titanium surfaces
20th European Conference on Biomaterials, Nantes, September 2006
R. Lange, F. Lüthen, B. Nebe, J. Rychly, U. Beck
E-MRS Fall Meeting, Warschau, September 2006
U. Beck, R. Lange, H.-G. Neumann
Micro- and nanoscaled titanium surface structures textured by electrolytic plasma and etching methods
THERMEC’, Vancouver, Juli 2006
U. Beck, R. Lange, H.-G. Neumann
New micro- and nanoscaled titanium surface structures textured by electrochemical methods
E-MRS Spring Meeting, Nice, Mai 2006
R. Lange, F. Lüthen, B. Nebe, J. Rychly, U. Beck
Critical reflection of the statistical correlation between biomaterial and cellular parameters
2. Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2006
B. Nebe, F. Lüthen, R. Lange, A. Ewald, U. Bulnheim, J. Rychly, U. Beck
Interaction of cells with implant surfaces
Symposium Biomaterialien in der HNO-Medizin, Rostock, September 2005
U. Beck, R. Lange, H.-G. Neumann
Ti-implant surfaces textured by micro-plasma
19th European Conference on Biomaterials, Sorrento, September 2005
U. Beck, R. Lange, H.-G. Neumann
Nanostructures on titanium surfaces produced by micro-plasma
12th International Conference on Composites/Nano Engineering, Teneriffa, Aug. 2005
U. Beck, R. Lange, H.-G. Neumann
Micro-plasma textured Ti-implant surfaces
E-MRS Spring Meeting, Strasbourg, Juni 2005
R. Lange, F. Lüthen, A. Kirbs, A. Baumann, P. Müller, J. Rychly, B. Nebe, U. Beck
A contribution to the correlation between physico-chemical properties of micro structured implants and cell biological parameters
Symposium Biomaterialien in der Zahnmedizin, Rostock, September 2004
R. Lange, F. Lüthen, A. Kirbs, P. Müller, J. Rychly, B. Nebe, U. Beck
European Cells and Materials Conference V, Davos, Juni 2004
A. Kirbs, R. Lange, K. Schröder, A. Ohl, U. Beck
Electrochemical characterisation of thin titanium films on plasma pretreated PEEK substrats
7th World Biomaterials Congress, Sydney, May 2004
R. Lange, F. Lüthen, A. Kirbs, P. Becker, P. Müller, J. Rychly, B. Nebe, U. Beck
Correlation between biological parameters of cells on micro structured titanium surfaces and its topographical characteristics
18th European Conference on Biomaterials, Stuttgart, Oktober 2003
R. Lange, F. Lüthen, A.Kirbs, P. Becker, P. Müller, J. Rychly, U. Beck, B. Nebe
Correlation between morphological characteristics of microstructured surfaces of titanium implants and cell biological parameters
Internationales Symposium “Interface Biology of Implants”, Rostock, Mai 2003
R. Lange, P. Becker, A. Kirbs, F. Lüthen, B. Nebe, J. Rychly, H.-G. Neumann, U. Beck
Oberflächenmodifikationen medizinischer Implantate und ihre Charakterisierung
Jahrestagung der Deutschen Gesellschaft für Biomaterialien 2002, Dresden, November 2002
R. Lange, A. Kirbs, B. Nebe, J. Rychly, H.G. Neumann, U. Beck
Physical and chemical methods for the surface characterization of titanium implants
17th European Conference on Biomaterials, Barcelona, Spain, September 2002
B. Nebe, A. Diener, F. Lüthen, R. Lange, U. Beck, H.-G. Neumann, J. Rychly
The formation of cellular adhesions is controlled by the topography of titanium surfaces
17th European Conference on Biomaterials, Barcelona, Spain, September 2002
P. Becker, A. Baumann, U. Beck, A. Kirbs, J. Rychly, F. Lüthen, H.-G. Neumann
Protein adsorption on spark anodised titanium
17th European Conference on Biomaterials, Barcelona, Spain, September 2002
A. Kirbs, R. Lange, U. Beck
Methods for the physical and chemical characterisation of surfaces of titanium implants
BioCon Valley 2002, Rostock – September 2002, Vortrag
R. Lange, A. Kirbs, B.Nebe, F. Lüthen, J. Rychly, A. Baumann, H.-G. Neumann, U. Beck
Methods for the physico-chemical description of titanium implant surfaces
BioCon Valley 2002, Rostock – September 2002,
R. Lange, A. Kirbs, B. Nebe, P. Müller, J. Rychly, A. Baumann, H.-G. Neumann, U. Beck
On the determination of the fractal dimension of rough surfaces of titanium implants
BioCon Valley 2002, Rostock – September 2002
A. Kirbs, R. Lange, B.Nebe, F. Lüthen, J. Rychly, U. Beck
Methods for the physical and chemical characterisation of surfaces of titanium implants
E-MRS 2002, Strasbourg, Juni 2002
A. Kirbs, R. Lange, B. Nebe, J. Rychly, P. Müller, U. Beck
On the description of the fractal nature of micro structured surfaces of titanium-implants
E-MRS 2002, Strasbourg, Juni 2002
B. Nebe, F. Lüthen, H.-G. Neumann, R. Lange, U. Beck, J. Rychly
Zelle-Matrix-Wechselwirkung auf Titan-Oberflächen in Abhängigkeit von der Oberflächenrauhigkeit
Jahrestagung der Deutschen Gesellschaft für Biomaterialien 2001, Rostock, September 2001
R. Lange, A.Kirbs, J. Rychly, B. Nebe, U. Beck
Physikalisch – chemische Charakterisierung von strukturmodifizierten Titanimplantaten
Jahrestagung der Deutschen Gesellschaft für Biomaterialien 2001, Rostock, September 2001
U. Beck, A. Kirbs, R. Lange
Surface analysis of titanium implants with EIS
ECASIA’01, Avignon, Oktober 2001
R. Lange, F. Lüthen, U. Beck, J. Rychly, A. Baumann, B. Nebe
Cell-extracellular matrix interaction and physico-chemical characteristics of titanium surfaces depend on the roughness of the material
E-MRS 2001, Strasbourg, Juni 2001